GSK, Genmab Gain Approval for Arzerra

GSK and Genmab have received approval of Arzerra (ofatumumab) from the FDA for use in patients with chronic lymphocytic leukemia (CLL) that do not respond to fludarabine and alemtuzumab.

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By: Tim Wright

Editor-in-Chief, Contract Pharma

GSK and Genmab have received approval of Arzerra (ofatumumab) from the FDA for use in patients with chronic lymphocytic leukemia (CLL) that do not respond to fludarabine and alemtuzumab. Arzerra is a monoclonal antibody that causes the body’s immune response to fight against normal and cancerous B-cells. The approval is based on results from a study in which 42% of patients with CLL, who did not respond to both fludarabine and alemtuzumab (two therapies used in treating CLL), responded...

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